GLP-1: Uses, Overview and Considerations

A class of medications that mimic incretin hormones to regulate blood sugar and support weight management.

Medically reviewed

Updated 2026

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Milli provides educational information only about medications. We do not prescribe, recommend or endorse any drug. Never start, stop or change a medicine without a licensed doctor's guidance.

How they work

GLP-1 receptor agonists mimic the natural gut hormone GLP-1, improving insulin release, slowing gastric emptying, and reducing appetite.

Common uses

Type 2 diabetes management and, in specific cases, chronic weight management — always under a doctor's care.

Common side effects

Nausea, vomiting, constipation, and — rarely — pancreatitis. GLP-1s should not be used with a personal or family history of medullary thyroid carcinoma or MEN2.

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Educational content only

Milli's Health Library provides general educational information reviewed against peer-reviewed medical sources. It is not a diagnosis, prescription, or medical advice. Milli does not recommend medications. Always consult a licensed doctor before starting, stopping or changing any treatment.

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